Enhancement of proton therapy effectiveness experimentally demonstrated for the first time: Proton Boron Capture Therapy (PBCT)
The use of proton-boron nuclear fusion to enhance proton therapy effectiveness in the cancer cell killing rate has been demonstrated experimentally as a result of a scientific collaboration among researchers coming from Laboratori Nazionali del Sud (LNS-INFN) in Catania, ELI-Beamlines (ELI-IoP-ASCR) in Prague, Department of Physics of University of Naples Federico II (DoP-UoN), and Fondazione Bruno Kessler (FBK) in Trento. The experimental research, carried out at LNS, is a result of two years of intensive experimental activity based on trials with various cell lines.
Image: The CATANA tumor treatment room at LNS-INFN, Catania, Italy (courtesy of G. Agnello)
What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how important bioinorganic electron transfer systems operate. Using a combination of very different, time-resolved measurement methods, the scientists were able to show that so-called pre-distorted states can speed up photochemical reactions or make them possible in the first place. The group headed by Sonja Herres-Pawlis from the RWTH Aachen University (RWTH) Michael Rübhausen from the University of Hamburg and Wolfgang Zinth from Munich’s Ludwig Maximilian University, is presenting its findings in the journal Nature Chemistry.
From 1st January 2018, the new project of the ELI Beamlines research centre ADONIS has been launched. The name is an abbreviation derived from the title Advanced research using high intensity laser produced photons and particles. The project will run until the end of October 2022 and is funded by the Operational Program Research, Development and Education from the Excellence Research Challenge.
Over the past few days, the physical installation of the L3-HAPLS (Advanced Petawatt Laser System) was successfully finished. The L3-HAPLS was delivered from the Lawrence Livermore National Laboratory (LLNL) to ELI Beamlines in Dolní Břežany in June this year. Since the end of September, a joint team of scientific and technical staff from LLNL, the ELI Beamlines center of the Institute of Physics of the Academy of Sciences has worked intensively on the installation of the laser. After the connection and commissioning of cooling, vacuum, electrical and electronic systems of the laser, the first part of the laser chain has been put into operation. The first upgraded part of the L3-HAPLS system consists of an oscillator and a pump laser, which provide pulses with energy of 2 J and a repetition frequency of 10 Hz.
On November 1st, 2017, the vacuum compressor of PW laser pulses for the laser system L3 (one of the four lasers at ELI Beamlines) arrived in Dolní Břežany from Brno. It is the largest vacuum opto-mechanical unit ever designed and manufactured in the Czech Republic.
The Israeli Minister of Science, Technology and Space Ofir Akunis with his delegation visited the ELI Beamlines and HiLASE laser centres in Dolni Brezany on the 26th of June 2017.
On February 9th, 2017 a crucial milestone for the development of the ELIMED dosimetry section of the ELIMAIA beamline was achieved by the INFN-LNS team. ELIMED is the beam transport and dosimetry section of the ELI Multidisciplinary Applications for laser-Ion Acceleration (ELIMAIA) and represents a key technology for the entire ELI-Beamlines facility since it will enable users to perform pre-clinical research for future applications in cancer therapy, such as biological cell irradiation with short bunches of protons (not available at conventional facilities) accelerated by the HAPLS PW-class, 10 Hz laser.
You can read the new issue of the ELI Beamlines Newsletter right now and here. Have a nice reading!
The Institute of Physics of the Czech Academy of Sciences has gained another patent. The research team responsible for this result belongs to the ELI Beamlines research centre and this is the first patent application in the history of this project.
The High-Repetition-Rate Advanced Petawatt Laser System (HAPLS), being developed at Lawrence Livermore National Laboratory (LLNL), recently completed a significant milestone: demonstration of continuous operation of an all diode-pumped, high-energy femtosecond petawatt laser system.
The European Development Fund and the Czech Ministry of Education, Youth and Sports has awarded cca. 250 million CZK to the ELIBIO project at the new ELI Beamlines laser facility of the Institute of Physics of the Czech Academy of Sciences. The ELIBIO project explores new frontiers in light and optics to create breakthrough science in biology, chemistry, and physics. The project will bring world-leaders in photon science and structural biology to the Czech Republic.
Article published in Physical Review X by the ELIMAIA team.
On Thursday October 27th, 2016 we invited in our facility Prof. Arie Zigler from Faculty of Science of Hebrew University in Jerusalem and also he is a Full Professor at Racah Institute of Physics at Hebrew University of Jerusalem.