ELI had a strong presence with more than 40 contributions from Extreme Light Infrastructure Facilities (ELI Beamlines, Czech Republic and ELI ALPS, Hungary) in the form of invited talks, poster presentations, and technical discussions. The contributions covered a wide range of topics, from facility updates and strategic developments at the ELI Facilities, commissioning of advanced laser systems and target stations to breakthroughs in particle acceleration, plasma diagnostics, and AI-driven control systems for research infrastructures.

Among the ELI highlights was an invited talk about laser-driven particle beams for extreme selective dose delivery in cancer therapy by Katalin Hideghéty which explored the promise of laser-accelerated electrons, protons, and neutrons for highly targeted cancer treatment. These ultra-precise beams offer the potential to minimise damage to healthy tissue while delivering powerful doses to tumors.
Both of these experiments showcase the potential of using laser-driven particle beams for more targeted and advanced cancer therapies in the future.

ELI’s strong presence at SPIE 2025 demonstrates the growing results of the open-access research facility. With state-of-the-art lasers, unique experimental platforms, and a dynamic international user community, ELI is applying increasingly collaborative, application-driven developments which are contributing to solving real-world challenges in medicine, materials, and beyond.